In traditional clinical studies, patients are often unnecessarily exposed to a placebo comparator arm. Placebos increase the burden on both patients and sites. They are not only associated with ethical challenges, but also require higher numbers of patients to complete trials.
Working towards reducing and ultimately eliminating the use of placebo comparator arms should be an industry-wide goal. Phesi works to support this aim with the use of synthetic data via an integrated and systematic approach. Synthetic data is collated from similar or identical trials using the same agent, with real-world patient data, to accurately model comparator outcomes while accelerating development.